State of the Union guests reflect nation's hot-button issues

Several lawmakers are bringing special guests to President Obama's State of the Union address Tuesday night in order to make a statement.

Several lawmakers are bringing guests to help underscore the importance of gun control. More than 20 House Democrats are bringing guests who have been personally affected by gun violence. A bipartisan pair of Arizona lawmakers, meanwhile, will host former Rep. Gabrielle Giffords, D-Ariz., and her husband Mark Kelly.

Other lawmakers are bringing guests tied to issues like immigration and voting rights.

Below is a partial list of officials and the guests they are bringing. CBS News will update the list as more guests are confirmed:

First Lady Michelle Obama:

• Lt. Brian Murphy, who was wounded while responding to the Sikh Temple shooting last August in Oak Creek, Wisconsin. He was struck by 15 bullets.
• Cleopatra Cowley-Pendleton and Nathaniel Pendleton Sr., parents of 15-year-old Hadiya who was killed in a Chicago park.
• Desiline Victor, a 103-year-old Florida woman who waited in line for several hours to vote.
• Tim Cook, CEO of Apple.

House Minority Leader Pelosi:

• Mother and daughter from Newtown, Conn. The 4th grader sent Pelosi a letter asking for her support to strengthen gun laws in the wake of the Sandy Hook massacre.

Sen. John McCain, R-Ariz., and Rep. Ron Barber, D-Ariz.:

• Former Rep. Gabrielle Giffords, D-Ariz., and her husband Mark Kelly

Rep. Steve Stockman, R-Texas:

• Musician and gun advocate Ted Nugent

Sens. Richard Blumenthal, D-Conn., and Chris Murphy, D-Conn.:

• First Selectwoman Pat Llodra, a Republican and the Chief Executive Officer of Newtown
• Newtown Detectives Jason Frank and Dan McAnaspie, two of several first responders who rushed to Sandy Hook Elementary School on the day of the tragedy

Rep. Luis Gutierrez, D-Ill.:

• Undocumented immigrant Gabino Sanchez. The South Carolina husband and father of two U.S. citizen children is fighting deportation. Sanchez entered the country when he was 15 years old and has been working and living peacefully in the U.S. ever since.

Sen. Dianne Feinstein, D-Calif.:

• Josh Stepakoff, who in 1999 was shot at the North Valley Jewish Community Center in Granada Hills, Calif. Stepakoff, now 20, is a student at California State University Northridge.

Sen. Frank Lautenberg, D-N.J.:

• Matt Gross, a New Jersey native who was shot in the head in 1997, at the age of 27. Gross was one of several victims wounded during a shooting attack on the observation deck of the Empire State Building.

More House Democrats bringing guests affected by gun violence:

Rep. Jim Langevin, R.I.

Rep. Keith Ellison, Minn.

Rep. Carolyn McCarthy, N.Y.

Rep. Rosa DeLauro, Conn.

Rep. David Cicilline, R.I.

Rep. Diana DeGette, Colo.

Rep. Tammy Duckworth, Ill.

Rep. Elizabeth Esty, Conn.

Rep. Lois Frankel, Fla.

Rep. Lujan Grisham, N.M.

Rep. Janice Hahn, Calif.

Rep. Jim Himes, Conn.

Rep. Alan Lowenthal, Calif.

Rep. Gloria Negrete-McLeod, Calif.

Rep. Eleanor Holmes Norton, D.C.

Rep. Ed Perlmutter, Colo.

Rep. Jan Schakowsky, Ill.

Rep. Brad Schneider, Ill.

Rep. Bobby Scott, Va.

Rep. Mike Thompson, Calif.

Rep. Krysten Sinema, Ariz.

Rep. Chris Van Hollen, Md.

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North Korean Tremor Raises Fear of Nuke Test

A large tremor measured at magnitude 4.9 was detected in North Korea and governments in the region scrambled to determine whether it was a nuclear test that the North Korean regime has vowed to carry out despite international protests.

Japan's prime minister has called an urgent security meeting, according to chief government spokesman Yoshihide Suga, and South Korea raised its military alert level, the AP reported.

Suspicions were aroused when the U.S. Geological Survey said it had detected a magnitude 4.9 earthquake Tuesday in North Korea.

The Comprehensive Test Ban Treaty Organization told ABC News, "We confirm that a suspicious seismic event has taken place in North Korea." The agency said it was trying to confirm the nature of the tremor.

North Korea Threatens More Nuclear Tests, Warns U.S. Watch Video

"The event shows clear explosion-like characteristics and its location is roughly congruent with the 2006 and 2009 DPRK (North Korea) nuclear tests," said Tibor Toth, executive secretary of the organization.

"If confirmed as a nuclear test, this act would constitute a clear threat to international peace and security, and challenges efforts made to strengthen global nuclear disarmament and non-proliferation," Toth said in a statement on the organization's web site.

Kim Min-seok, a South Korean Defense Ministry spokesman, told reporters that North Korea informed United States and China that it intended to carry out another nuclear test, according to the AP. But U.S. officials did not respond to calls from ABC News Monday night.

North Korea threatened in January to carry out a "higher-level" test following the successful Dec. 12 launch of a long range rocket. At the time, North Korea's leader Kim Jong-Un said his country's weapons tests were specifically targeting the United States.

The suspicious tremor comes just hours before President Obama is to give the State of the Union address, and it marks the first diplomatic test in the region for new Secretary of State John Kerry.

China, North Korea's main ally in the region, has warned North Korea it would cut back severely needed food assistance if it carried out a test. Each year China donates approximately half of the food North Korea lacks to feed its people and half of all oil the country consumes.

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Liver cancer survival time tripled by virus

The virus used in the vaccine that helped eradicate smallpox is now working its magic on liver cancer. A genetically engineered version of the vaccinia virus has trebled the average survival time of people with a severe form of liver cancer, with only mild, flu-like side effects.

Thirty people with hepatocellular carcinoma received three doses of the modified virus – code-named JX-594 – directly into their liver tumour over one month. Half the volunteers received a low dose of the virus, the other half a high dose. Members of the low and high-dose groups subsequently survived for, on average, 6.7 and 14.1 months respectively. By contrast, trials several years ago showed that sorafenib, the best existing medication for this cancer, prolonged life by only three months.

Two of the patients on the highest viral dose were still alive more than two years after the treatment. "It's a very substantial survival benefit," says Laurent Fischer, president of Jennerex, the company in San Francisco developing the treatment under the trade name Pexa-Vec.

Besides shrinking the primary tumour, the virus was able to spread to and shrink any secondary tumours outside the liver. "Some tumours disappeared completely, and most showed partial destruction on MRI scans," says David Kirn, head of the study at Jennerex. Moreover, the destruction was equally dramatic in the primary and secondary tumours.

"This clinical trial is an exciting step forward to help find a new way of treating cancers," says Alan Melcher of the University of Leeds, UK, who was not involved in the study. "It helps demonstrate the cancer-fighting potential of viruses, which have relatively few side effects compared with traditional chemo or radiotherapy," he says. "If it proves effective in larger trials, it could be available to patients within five years."

The fact that the virus appears able to spread to secondary tumours suggests that simply injecting the virus into the bloodstream may be effective. A trial to compare this treatment with injecting the virus directly into a tumour is under way.

Targeted at cancer

The virus has had a gene coding for an enzyme called thymidine kinase snipped out. The enzyme enables the virus to recognise and infect dividing cells. By removing the gene, the virus's developers have reduced the likelihood of healthy dividing cells being infected.

Instead, the virus exclusively attacks cancerous tissue, by targeting two genes that have increased activity in tumour cells. One genes is associated with an epidermal growth factor receptor, which stimulates the cancer to grow. The other is associated with a vascular endothelial growth factor, which enables the cancer to recruit its own blood supply. The virus reduces the activity of both genes, causing the infected cancer cell to wither and die.

What's more, the virus carries extra genes to prod the body's own immune system into action against the cancer. One produces granulocyte colony stimulating factor, a protein that encourages production of extra white blood cells at sites of infection. The other produces a protein not naturally found in humans, called Lac-Z, that earmarks infected cells for destruction.

Fischer says that to date, more than 200 people have received the virus, which has also shown promise against other types of cancer, including those of the kidney and skin. But he warns that not everyone sees a benefit. "We know why patients respond, but not why they don't," he says.

Journal reference: Nature Medicine, DOI: 10.1038/nm.3089

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First Singaporean nominated for Grammy falls short

LOS ANGELES - The first Singaporean to be nominated for a Grammy came up short on Sunday, with guitarist Arun Shenoy losing out to top veteran trumpeter Chris Botti for best pop instrumental album.

Shenoy, who was born in the southern Indian state of Karnataka before moving to Singapore, received a Grammy nomination for his debut album "Rumbadoodle," which he recorded during live performances around the world.

Shenoy has described his guitar work as a new perspective on gypsy rumba flamenco, merging the genre with other global influences.

The Grammy ultimately went to "Impressions" by Botti, whose pop-influenced jazz works had won him four previous nominations.

The other contenders in the category -- saxophonist Dave Koz, for a live album recorded in Tokyo, and guitarist Larry Carlton -- also had previous Grammy nominations.

- AFP/ir

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Almost famous: See celebs' early roles

By Henry Hanks, CNN

updated 5:05 PM EST, Thu February 7, 2013

Stars who started out like GoDaddy's geek

Jesse Heiman

Sylvester Stallone

John Travolta

Keanu Reeves

Courtney Cox

Matt LeBlanc

Tina Fey

Rainn Wilson

Megan Fox

Dean Winters

Read More..

Tornado rips through Miss. city, causes major damage

HATTIESBURG, Miss. An apparent tornado tore through Hattiesburg on Sunday as part of a wave of severe storms that downed trees, damaged buildings and caused at least several injuries.

The twister traveled down one of Hattiesburg's main streets and caused what officials described as major damage, officials said, hitting several buildings on the campus of the University of Southern Mississippi. Kyle Hopkins, emergency operations director for surrounding Forrest County, said officials hadn't confirmed injuries. There were reports of several people hurt elsewhere in the state.

"We had a tornado touch down. We have a lot of damage," Hopkins said.

The university released a statement saying that several buildings had been damaged but that no injuries were reported. Campus police have declared a state of emergency and asked anyone not on campus to stay away.

Video by CBS affiliate WHLT-TV shows the heavy damage to the university, including busted windows, wood panels strewn on the lawn and fallen fences.

The storm overturned and damaged vehicles and threw debris around parts of the campus.

To the west, Marion County emergency director Aaron Greer says three injuries have been reported in the community of Pickwick, about seven miles south of Columbia. He says two people were taken to hospitals, but the third didn't have the injury examined.

Greer says one mobile home was destroyed, three other structures have major damage and several have minor damage.

National Weather Service meteorologist Joanne Culin says there have also been reports of injuries in Marion County.

Nasty weather has settled in on much of Louisiana and Mississippi, including tornado or flash flood watches.

The National Weather Service says bad weather is likely to stretch into Fat Tuesday in southeast Louisiana. Jefferson Parish has canceled a Monday night parade.

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Possible Dorner Sighting Leads to Store Evacuation

A Northridge, Calif., home improvement store was evacuated tonight because of a possible sighting of suspected cop-killer Christopher Dorner, just hours after police announced a $1 million reward for information leading to his arrest.

As helicopters hovered overhead and a command center was established, police searched the Lowe's store and eventually told shoppers they could leave, but could not take their cars out of the parking lot.

LAPD spokesman Gus Villanueva said the major response to the possible sighting was a precaution, but couldn't say whether Dorner was in the area.

The announcement of the $1 million reward today came as authorities in Big Bear, Calif., scaled back their search for Dorner, the disgruntled ex-cop who is suspected in three revenge killings.

"This is the largest local reward ever offered, to our knowledge," Los Angeles Police Chief Charlie Beck said at a news conference today. "This is an act of domestic terrorism. This is a man who has targeted those that we entrust to protect the public. His actions cannot go unanswered."

The money for the reward was pooled by businesses, government, local law enforcement leaders and individual donors, Beck said.

PHOTOS: Former LAPD Officer Suspected in Shootings

The reward comes on the fourth day of a manhunt for Dorner, who has left Southern California on edge after he allegedly went on a killing spree last week to avenge his firing from the police force. Dorner outlined his grievances in a 6,000 word so-called "manifesto" and said he will keep killing until the truth is known about his case.

Irvine Police Department/AP Photo

Manhunt for Alleged Cop Killer Heads to California Mountains Watch Video

Christopher Dorner Search: Officials Search for Ex-officer in the Mountains Watch Video

Dorner's threats have prompted the LAPD to provide more than 50 law enforcement families with security and surveillance detail, Beck said.

Authorities are chasing leads, however they declined to say where in order to not impede the investigation.

Dorner's burned-out truck was found Thursday near Big Bear Lake, a popular skiing destination located 80 miles northeast of Los Angeles.

Investigators found two AR-15 assault rifles in the burned-out truck Dorner abandoned, sources told ABC News.

The truck had a broken axle, which may be the reason he decided to set fire to it, the police sources said.

Full Coverage: Christopher Jordan Dorner

Officers have spent the past couple of days going door-to-door and searching vacant cabins. The manhunt was scaled back to 25 officers and one helicopter in the resort town today, according to the San Bernadino Sheriff's Office.

On Saturday, Beck announced he would reopen the investigation into Dorner's firing but said the decision was not made to "appease" the fugitive ex-cop.

"I feel we need to also publicly address Dorner's allegations regarding his termination of employment, and to do so I have directed our Professionals Standards Bureau and my Special Assistant for Constitutional Policing to completely review the Dorner complaint of 2007; To include a re-examination of all evidence and a re-interview of witnesses," Beck said. "We will also investigate any allegations made in his manifesto which were not included in his original complaint."

Dorner is suspected of killing Monica Quan and her fiancé Keith Lawrence last Sunday in their car in the parking lot of their Irvine, Calif., condominium complex. Both were struck with multiple gunshot wounds.

Quan's father, Randal Quan, was a retired captain with the LAPD and attorney who represented Dorner before a police review board that led to Dorner's dismissal from the force in 2008.

On Wednesday, after Dorner was identified as a suspect in the double murder, police believe he ambushed two Riverside police officers, killing one and wounding the other.

The next day, Randal Quan reported he received a taunting call from a man claiming to be Dorner who told him that he "should have done a better job of protecting his daughter," according to court documents documents.

Anyone with information leading to the arrest of Christopher Dorner is asked to call the LAPD task force at 213-486-6860.

ABC News' Dean Schabner, Jack Date, Pierre Thomas, Jason Ryan and Clayton Sandell and The Associated Press contributed to this report.

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Sooty ships may be geoengineering by accident

GEOENGINEERING is being tested - albeit inadvertently - in the north Pacific. Soot from oil-burning ships is dumping about 1000 tonnes of soluble iron per year across 6 million square kilometres of ocean, new research has revealed.

Fertilising the world's oceans with iron has been controversially proposed as a way of sucking carbon dioxide out of the atmosphere to curb global warming. Some geoengineers claim releasing iron into the sea will stimulate plankton blooms, which absorb carbon, but ocean processes are complex and difficult to monitor in tests.

"Experiments suggest you change the population of algae, causing a shift from fish-dominated to jellyfish-dominated ecosystems," says Alex Baker of the University of East Anglia, UK. Such concerns led the UN Convention on Biological Diversity (CBD) to impose a moratorium on geoengineering experiments in 2010.

The annual ship deposition is much larger, if less concentrated, than the iron released in field tests carried out before the moratorium was in place. Yet because ship emissions are not intended to alter ocean chemistry, they do not violate the moratorium, says Jim Thomas of the ETC Group, a think tank that consults for the CBD. "If you intentionally drove oil-burning ships back and forth as a geoengineering experiment, that would contravene it."

The new study, by Akinori Ito of the Japan Agency for Marine-Earth Science and Technology, is the first to quantify how shipping deposits iron in parts of the ocean normally deficient in it. Earlier models had assumed that only 1 to 2 per cent of the iron contained in aerosols, including shipping emissions, is soluble in seawater, so the remaining 98 to 99 percent would sink to the bottom without affecting ocean life. But Ito found that up to 80 per cent of the iron in shipping soot is soluble (Global Biogeochemical Cycles, doi.org/kdj). As this soot rapidly falls to the sea surface, it is likely to be fertilising the oceans.

In the high-latitude north Pacific - a region that is naturally iron-poor and therefore likely to be most affected by human deposits - ship emissions now account for 70 per cent of soluble iron from human activity, with the burning of biomass and coal accounting for the rest. Shipping's share will rise as traffic continues to grow and regulations restrict coal and biomass emissions.

Can we learn anything from this unintentional experiment? Baker thinks not. "The process isn't scientifically useful," he says, because the uncontrolled nature of the iron makes it difficult to draw meaningful comparisons.

The depositions are unlikely to be harmful at current levels, he says, but "given the uncertainties, I just don't know how much these iron emissions would have to increase before there was demonstrable harm to an ecosystem, or benefit in terms of carbon uptake, for that matter".

This article appeared in print under the headline "Ships inadvertently fertilise the oceans"

If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.

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Merkel counts cost as minister quits in election year

BERLIN, Germany: German Chancellor Angela Merkel was left licking her wounds on Sunday after her education minister quit amid a plagiarism scandal, depriving her of a key ally as she gears up for September elections.

Merkel betrayed rare emotion as she accepted "with a very heavy heart" the resignation of Annette Schavan, a personal friend, who quit to fight charges from her former university that she plagiarised her thesis 33 years ago.

Although Merkel enjoys a sizeable lead in the polls and a high level of personal popularity, this is the second body blow in recent weeks after what she termed a "painful" loss in a state election on January 20.

"The year could hardly have started worse for Mrs Merkel," gloated the chief whip of the opposition Social Democratic Party (SPD), Thomas Oppermann.

Nevertheless, the level of alleged plagiarism in Schavan's thesis "Person and Conscience" was thought to be much less than in a similar case two years ago when popular defence minister Karl-Theodor zu Guttenberg quit.

And even some opposition figures showed some sympathy for Schavan, who has vowed to fight Duesseldorf University's decision to strip her of her doctorate in the courts.

SPD head Sigmar Gabriel said in an interview in the Welt am Sonntag weekly that he valued Schavan as an "honest and competent" minister and he was "extremely sorry" to see her go but he believed it was the right decision.

The media was full of praise for the manner of Schavan's departure, perceived as dignified, and for the way she appeared to put her party and Merkel ahead of her personal ambition.

Addressing her leader and friend as "dear Angela", Schavan said the accusations that she cheated affected her "deeply" and said her priorities had always been "first my country, then my party and then me personally".

Merkel has already survived zu Guttenberg's more damaging resignation; the loss of another defence minister over controversial comments on Afghanistan; and the departure of party ally Christian Wulff as president over a home loan scandal.

Several media reports said the loss of Schavan would not inflict too much damage on Merkel, even in the run-up to elections on September 22.

"Merkel can distinguish between the demands of her office and of friendship. The office demanded a quick, concise decision. Friendship demanded glowing words. She offered... both," said the Berlin-based Tagesspiegel daily.

"That makes Merkel unassailable in this case because no-one could have done it better," added the paper.

The left-leaning Sueddeutsche Zeitung said the resignation "will not harm Merkel".

"Until now, no resignation has been seen by the people as due to her own political failings. There were always individual reasons. That is the art that Merkel has mastered. Everything bounces off her," noted the paper.

"In this case, that is completely right."

The chancellor moved quickly to mitigate the fallout, immediately appointing the 61-year-old Johanna Wanka, a mathematician with wide experience in education, as the new minister.

But the influential Die Zeit weekly noted that things were getting "lonely" around Merkel, as she loses yet another ally from her own conservative ranks amid a loveless relationship with her coalition partner, the Free Democrats.

"With Schavan's resignation, Merkel loses a further faithful ally. There aren't many people around her that can help her," said the paper.

"Like (former chancellor Helmut) Kohl at the end of his long chancellorship, she's standing almost completely on her own. There's hardly anyone left from her Praetorian guard."

- AFP/al

Read More..

Almost famous: See celebs' early roles

By Henry Hanks, CNN

updated 5:05 PM EST, Thu February 7, 2013

Stars who started out like GoDaddy's geek

Jesse Heiman

Sylvester Stallone

John Travolta

Keanu Reeves

Courtney Cox

Matt LeBlanc

Tina Fey

Rainn Wilson

Megan Fox

Dean Winters

Read More..